From Albany Airport:
Start out going NORTHWEST on CR-151 / ALBANY SHAKER RD toward NY-155 / CR-153 / WOLF RD. Merge onto I-87 S via the ramp on the LEFT. Take the I-90 E / I-87 S / I-90 W exit- EXIT 1- toward ALBANY / BOSTON / NEW YORK / BUFFALO / NEW YORK THRUWAY. Merge onto NEW YORK STATE TRWY S / I-90 W via EXIT 1W toward NEW YORK / BUFFALO / NEW YORK THRUWAY (Portions toll). Merge onto I-890 W via EXIT 25 toward SCHENECTADY / RT-7 / RT-146 (Portions toll). Take the MICHIGAN AVE exit- EXIT 6. Turn RIGHT onto S BRANDYWINE AVE. Turn LEFT onto NY-5 / STATE ST. Turn RIGHT onto BARRETT ST. End at 530 Franklin St.

From Buffalo and Syracuse:
Merge onto I-90 E / NEW YORK STATE TRWY E via EXIT 6 toward ALBANY (Portions toll). Merge onto I-890 E via EXIT 26 toward SCHENECTADY. Take EXIT 4B toward ERIE BLVD. Turn SLIGHT LEFT onto WASHINGTON AVE. Turn SLIGHT RIGHT onto STATE ST. Turn LEFT onto BARRETT ST. End at 530 Franklin St.

From Boston:
Merge onto I-90 W (Portions toll). Merge onto NEW YORK STATE TRWY W (Portions toll). Merge onto NEW YORK STATE TRWY N / I-87 N toward I-90 / ALBANY / BUFFALO (Portions toll). NEW YORK STATE TRWY N / I-87 N becomes NEW YORK STATE TRWY W / I-90 W (Portions toll). Merge onto I-890 W via EXIT 25 toward SCHENECTADY / RT-7 / RT-146 (Portions toll). Take the MICHIGAN AVE exit- EXIT 6. Turn RIGHT onto S BRANDYWINE AVE. Turn LEFT onto NY-5 / STATE ST. Turn RIGHT onto BARRETT ST. End at 530 Franklin St.

From Montreal & Plattsburgh:
Merge onto I-87 S via the ramp on the LEFT. Take the I-90 E / I-87 S / I-90 W exit- EXIT 1- toward ALBANY / BOSTON / NEW YORK / BUFFALO / NEW YORK THRUWAY. Merge onto NEW YORK STATE TRWY S / I-90 W via EXIT 1W toward NEW YORK / BUFFALO / NEW YORK THRUWAY (Portions toll). Merge onto I-890 W via EXIT 25 toward SCHENECTADY / RT-7 / RT-146 (Portions toll). Take the MICHIGAN AVE exit- EXIT 6. Turn RIGHT onto S BRANDYWINE AVE. Turn LEFT onto NY-5 / STATE ST. Turn RIGHT onto BARRETT ST. End at 530 Franklin St.

From NYC:
Take the NYS Thruway north to I-87. Take the I-90 E / I-87 S / I-90 W exit- EXIT 1- toward ALBANY / BOSTON / NEW YORK / BUFFALO / NEW YORK THRUWAY. Merge onto NEW YORK STATE TRWY S / I-90 W via EXIT 1W toward NEW YORK / BUFFALO / NEW YORK THRUWAY (Portions toll). Merge onto I-890 W via EXIT 25 toward SCHENECTADY / RT-7 / RT-146 (Portions toll). Take the MICHIGAN AVE exit- EXIT 6. Turn RIGHT onto S BRANDYWINE AVE. Turn LEFT onto NY-5 / STATE ST. Turn RIGHT onto BARRETT ST. End at 530 Franklin St.

From Binghamton:
Take I-88 North to I-90 East. Merge onto I-890 E via EXIT 26 toward SCHENECTADY. Take EXIT 4B toward ERIE BLVD. Turn SLIGHT LEFT onto WASHINGTON AVE. Turn SLIGHT RIGHT onto STATE ST. Turn LEFT onto BARRETT ST. End at 530 Franklin St.